- MEN pathway Mutants
- tem1∆
- tem1∆ net1-ts
- tem1-ts GAL-CDC15
- tem1-ts multicopy CDC14
- cdc15∆
- cdc15-ts multicopy TEM1
- cdc15-ts multicopy CDC14
- cdc15∆ net1-ts
- cdc15∆ net1-ts cdh1∆
- TAB6-1 cdc15∆
- GAL-TEM1
- mad2∆ GAL-TEM1 in nocodazole
- Multi-copy CDC15
cdc15-ts multicopy TEM1
debug: ,
test user =
test db =
Simulation:
Change of parameters: kkpnet"=0, TEM1T=20 (=20 copies)
Arrest: Telophase arrest.
Experiments:
Jaspersen, S.L., Charles, J.F., Tinker-Kulberg, R.L., and Morgan, D.O. (1998). A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae. Mol. Biol. Cell 9:2803-2817.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Table 2, tem1∆ cannot be rescued by Cdc15 over-expression.
Comments: